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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
11.52
Human Site:
S410
Identified Species:
25.33
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
S410
P
R
R
D
L
G
N
S
I
K
H
R
F
S
T
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
S386
P
R
R
D
L
G
N
S
I
K
H
R
F
S
T
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
D334
R
T
E
S
V
P
C
D
I
N
N
P
L
R
K
Dog
Lupus familis
XP_853953
898
99758
T404
P
Q
P
R
L
R
R
T
E
S
V
P
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
S411
P
R
R
D
L
G
N
S
I
K
H
R
F
S
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
S335
P
P
I
L
P
S
P
S
P
S
K
S
I
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
H408
D
L
G
N
S
I
K
H
R
F
S
T
K
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
C311
A
N
R
V
P
M
L
C
Q
P
F
P
M
D
S
Honey Bee
Apis mellifera
XP_393005
895
100160
D384
M
T
T
C
D
Y
C
D
K
Q
M
F
I
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
S350
K
V
V
V
P
I
G
S
L
S
V
G
L
C
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
100
N.A.
N.A.
0
13.3
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
20
26.6
N.A.
100
N.A.
N.A.
0
13.3
N.A.
6.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
19
10
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
28
10
0
0
19
0
0
0
0
0
19
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
10
28
0
0
% F
% Gly:
0
0
10
0
0
28
10
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
28
0
0
0
0
% H
% Ile:
0
0
10
0
0
19
0
0
37
0
0
0
19
0
19
% I
% Lys:
10
0
0
0
0
0
10
0
10
28
10
0
10
0
10
% K
% Leu:
0
10
0
10
37
0
10
0
10
0
0
0
19
0
0
% L
% Met:
10
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
10
0
10
0
0
28
0
0
10
10
0
0
0
0
% N
% Pro:
46
10
10
0
28
10
10
0
10
10
0
28
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
10
28
37
10
0
10
10
0
10
0
0
28
0
10
10
% R
% Ser:
0
0
0
10
10
10
0
46
0
28
10
10
10
28
10
% S
% Thr:
0
19
10
0
0
0
0
10
0
0
0
10
0
0
37
% T
% Val:
0
10
10
19
10
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _